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1 article(s) from Hwang, Patrick

Nanodiamond-DGEA peptide conjugates for enhanced delivery of doxorubicin to prostate cancer

Amanee D Salaam,
Patrick Hwang,
Roberus McIntosh,
Hadiyah N Green,
Ho-Wook Jun and
Derrick Dean

Beilstein J. Nanotechnol. 2014, 5, 937–945, doi:10.3762/bjnano.5.107

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Scheme 1: Nanodiamond-DGEA peptide conjugation. The carbodiimide reaction used EDAC and sulfo NHS to form a s...

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Scheme 2: Preparation of ND-DGEA+DOX system. After conjugation of DGEA peptide to NDs, DOX was adsorbed to th...

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Figure 1: Absorbance spectra for (a) DGEA before and after conjugation with ND and (b) DOX before and after a...

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Figure 2: Transmission electron microscope images of ND, ND-DGEA, and ND-DGEA+DOX. Arrows identify the layer ...

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Figure 3: FTIR spectra of ND, ND-DGEA conjugates, and DGEA peptide. The presence of characteristic peaks for ...

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Figure 4: Zeta potential and hydrodynamic size of ND, ND-DGEA, and ND-DGEA+DOX.

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Figure 5: Representative merged bright field and fluorescent microscopy images of hMSCs (A) and PC3 cells (B)...

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Figure 6: MTS assay of cell viability after 32 h exposure to various treatments. PC3 cells were treated with ...

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Published 01 Jul 2014

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